Sassuolo vs AC Milan prediction 11.10.2026 | Serie A

Alberto Aquilani's side have collected seven points from their first five matches, with nearly all of those points being collected at Mapei Stadium. Their home record is particularly encouraging: they defeated Torino 2-1 and Juventus 3-2 in their two home league games so far. 

Vasilije Adžić has been one of the standout performers, scoring three goals in his first five appearances. Sebastiano Esposito and Domenico Berardi also provide significant attacking threat, while Armand Laurienté has registered 19 shots and 1.14 xG. 

Sassuolo's last outing ended in a 2-1 defeat at Monza, meaning they will be looking to respond immediately after the international break. No suspensions were reported following that match.

But the host will be without several players due to injury, including Edoardo Pieragnolo, Fali Candé, Ismaël Koné, Jay Idzes, Daniel Boloca and Cristian Volpato, although some other absentees remain doubts ahead of the match.

Milan have made the stronger start and sit just a couple of points behind the leading trio. Rúben Amorim’s men could very well challenge for the Scudetto this season, as suggested by their unbeaten record at this early stage of the campaign.

Christian Pulisic scored in the 3-0 victory over Lecce before the break, while Diego Moreira has emerged as another important attacking contributor. Balancing Serie A fixtures with European football will be a challenge, though, but the Rossoneri have a deep enough squad to compete in both competitions.

The main injury concern is Alexis Saelemaekers, who is expected to miss the match after Milan confirmed that his previously operated right ankle has lost stability following a recent training injury. Further specialist assessment is ongoing, with no return date announced. 

Pulisic, meanwhile, was pictured training at Milanello this week, suggesting he remains available following his recent return from injury.