Mainz vs Bayer Leverkusen prediction 10.10.2026 | Bundesliga

Mainz return to competitive action after securing a dramatic 4:3 victory against Borussia Monchengladbach before the international break. 

In a topsy-turvy contest, Danny da Costa’s 89th minute goal secured a remarkable comeback victory for Urs Fischer’s side.

Die Nullfünfer maintained their winning form during the international break with a comfortable 3:0 friendly victory against Waldhof Mannheim. Ransford Konigsdorffer, Sheraldo Becker and Benedict Hollerbach scored in another excellent away showing.

Mainz have made an impressive start to the German domestic campaign, particularly on the road. Die Nullfünfer claimed a commanding 5:0 win at Hamburg, and a dominant 9:0 DFB Pokal win at VfB 1921 Krieschow.

Fischer’s men have now scored 19 goals in just five domestic fixtures, but they have failed to win both of their last two home Bundesliga matches.

A poor home record remains a concern for the hosts. Mainz lost four of their last five Bundesliga games at MEWA Arena since the end of last season. 

Mainz have also endured a poor record in recent games against Bayer. Die Nullfünfer failed to win any of their last six matches, with Leverkusen victorious in four of those fixtures.

Head coach Fischer remains unable to call on Dominik Kohr and Silas, while Robin Zentner is doubtful with a hand injury.

Paul Nebel, Silvan Widmer and Fabio Gruber returned to training this week and could be available on Saturday.

Bayer Leverkusen travel to Mainz after securing an impressive 2:0 victory against RB Leipzig before the international break.

Patrik Schick opened the scoring before Miguel Gutierrez completed a deserved win for Carles Martinez’s side.

Leverkusen have responded well since suffering a 3:2 defeat at Elversberg on the opening weekend of the Bundesliga season. The visitors won three and drew one of their next four competitive fixtures, keeping three clean sheets in that period.

Seven points from four league games leave Bayer fifth in the table, one position above Mainz.

While Leverkusen have been excellent at the BayArena, they remain winless on the road in the Bundesliga. Martinez’s men lost at Elversberg before throwing away a two-goal advantage in a 2:2 draw at Augsburg.

Head coach Martinez has some injury worries this weekend. Guela Doue and Kennet Eichhorn are expected to miss Saturday’s contest. Eliesse Ben Seghir, Montrell Culbreath and Christian Kofane are also considered doubtful.

Czech forward Schick should continue to spearhead the Leverkusen attack after scoring in all four Bundesliga fixtures this season.