Contents
- Competition: Champions League
 - Date: 5th October 2025
 - Kick-off: 20:00 UK / 21:00 CET
 - Venue: Estádio da Luz
 
Benfica welcome Bayer 04 Leverkusen to Lisbon on Wednesday night as both sides look to register their first win in the Champions League this season. As Águias boast just one point from three games, while Leverkusen have two after drawing two and losing one of their three encounters. Our preview covers Benfica vs Leverkusen predictions, betting tips and team news.
Benfica vs Bayer Leverkusen Head to Head (H2H) stats
- 
				
Benfica
0 : 0
Bayer Leverkusen
Champions League
 - 
				
Bayer Leverkusen
3 : 1
Benfica
Champions League
 - 
				
Benfica
2 : 1
Bayer Leverkusen
Europa League
 - 
				
Bayer Leverkusen
0 : 1
Benfica
Europa League
 
Benfica and Leverkusen have played each other four times before, all of which took place between 2013 and 2014. The Lisbon club avoided defeat in all four fixtures, winning two and keeping two clean sheets, while two games ended in a draw. The average number of goals per game was 1.5.
		
			
		
	
Benfica team overview
Following his sacking by Fenerbahçe back in August, José Mourinho replaced Bruno Lage as head coach of Benfica and has made plenty of changes, especially in defence. The Eagles have won each of their last three domestic games, scoring 11 goals and also kept a clean sheet in as many games.
This form has not been on display in Europe this season with Benfica amassing only one point from three games so far. Their Champions League campaign got off to a shocking start with a 3:2 defeat to Qarabağ at this stadium.
Subsequent away losses against Premier League sides Chelsea and Newcastle followed. Having won two of their last three home Champions League games, the Eagles will be confident of securing their first European win of the season this week against Leverkusen.
Mourinho will not be able to call up on the services of Bruma this week due to an Achilles tendon injury. The Left-back is being accompanied in the treatment room by Amar Dedić who is dealing with a muscle problem.
Last matches of Benfica
- 
				
Vitoria Guimaraes
0 : 3
Benfica
Liga Portugal
 - 
				
Benfica
3 : 0
Tondela
Taça da Liga
 - 
				
Benfica
5 : 0
Arouca
Liga Portugal
 - 
				
Newcastle United
3 : 0
Benfica
Champions League
 - 
				
Chaves
0 : 2
Benfica
Taça De Portugal
 
Benfica lineup
Goalkeeper
- 
								
1
Anatoliy Trubin
 
Defenders
- 
								
26
Samuel Dahl
 - 
								
44
Tomás Araújo
 - 
								
30
Nicolás Otamendi
 - 
								
8
Fredrik Aursnes
 
Midfielders
- 
								
20
Richard Ríos
 - 
								
10
Heorhiy Sudakov
 - 
								
5
Enzo Barrenechea
 
Forwards
- 
								
25
Gianluca Prestianni
 - 
								
14
Vangelis Pavlidis
 - 
								
11
Dodi Lukébakio
 
		
			
		
	
Bayer Leverkusen team overview
Bayer 04 Leverkusen have also enjoyed a good run of form lately and have lost just two of their last 12 games across all competitions.
Die Werkself visited league leaders and champions Bayern last weekend, hoping to register their fifth consecutive league win.
Despite the Reds resting players such as Kane, Olise and Diaz, Kasper Hjulmand’s team lost whilst failing to score for the first time this season.
Defensive Midfielder Equi Fernández and right back Lucas Vázquez are out with ligament and muscular issues respectively. The pair is being accompanied in the treatment room by the likes of Axel Tape and Nathan Tella who are dealing with hamstring and knee injuries, respectively.
Last matches of Bayer Leverkusen
- 
				
Bayern Munich
3 : 0
Bayer Leverkusen
Bundesliga
 - 
				
SC Paderborn
1 : 3
Bayer Leverkusen
DFB Pokal
 - 
				
Bayer Leverkusen
2 : 0
SC Freiburg
Bundesliga
 - 
				
Bayer Leverkusen
2 : 7
PSG
Champions League
 - 
				
FSV Mainz
3 : 4
Bayer Leverkusen
Bundesliga
 
Bayer Leverkusen lineup
Goalkeeper
- 
								
1
Mark Flekken
 
Defenders
- 
								
12
Edmond Tapsoba
 - 
								
5
Loïc Badé
 - 
								
4
Jarell Quansah
 
Midfielders
- 
								
44
Jeanuël Belocian
 - 
								
24
Aleix García
 - 
								
8
Robert Andrich
 - 
								
13
Arthur
 
Forwards
- 
								
19
Ernest Poku
 - 
								
14
Patrik Schick
 - 
								
9
Claudio Echeverri
 
Prediction
Boasting a win and a clean sheet in each of their last three games, Benfica will be feeling confident ahead of Wednesday night's match against Bayer Leverkusen. However, the Germans have also been in great form recently, losing just two of their last 12 matches, a run that includes two Champions League draws. I am therefore expecting a close game that could end in a 1:1 draw.
Three reasons we expect under 3.5 goals in this game
- None of the last four meetings between Benfica and Leverkusen produced more than three goals.
 - Six of the last eight Champions League games of Bayer Leverkusen ended with under 3.5 goals.
 - Only one of the last ten games of Benfica has produced more than three goals.
 
Main prediction Benfica - Bayer Leverkusen
Under 3.5 goals
Best Odds:
Benfica vs Bayer Leverkusen standings in Champions League
| League Stage | P | W | D | L | 
							 
								
								G - A
								
							 
						 | 
						GD | Pts | |
|---|---|---|---|---|---|---|---|---|
| 1 | Paris Saint Germain | 3 | 3 | 0 | 0 | 13 - 3 | +10 | 9 | 
| 2 | FC Bayern München | 3 | 3 | 0 | 0 | 12 - 2 | +10 | 9 | 
| 3 | Inter | 3 | 3 | 0 | 0 | 9 - 0 | +9 | 9 | 
| 4 | Arsenal | 3 | 3 | 0 | 0 | 8 - 0 | +8 | 9 | 
| 5 | Real Madrid | 3 | 3 | 0 | 0 | 8 - 1 | +7 | 9 | 
| 6 | Borussia Dortmund | 3 | 2 | 1 | 0 | 12 - 7 | +5 | 7 | 
| 7 | Manchester City | 3 | 2 | 1 | 0 | 6 - 2 | +4 | 7 | 
| 8 | Newcastle United | 3 | 2 | 0 | 1 | 8 - 2 | +6 | 6 | 
| 9 | FC Barcelona | 3 | 2 | 0 | 1 | 9 - 4 | +5 | 6 | 
| 10 | Liverpool | 3 | 2 | 0 | 1 | 8 - 4 | +4 | 6 | 
| 11 | Sporting CP | 3 | 2 | 0 | 1 | 7 - 4 | +3 | 6 | 
| 12 | Chelsea | 3 | 2 | 0 | 1 | 7 - 4 | +3 | 6 | 
| 13 | Qarabağ | 3 | 2 | 0 | 1 | 6 - 5 | +1 | 6 | 
| 14 | Galatasaray | 3 | 2 | 0 | 1 | 5 - 6 | -1 | 6 | 
| 15 | Tottenham Hotspur | 3 | 1 | 2 | 0 | 3 - 2 | +1 | 5 | 
| 16 | PSV | 3 | 1 | 1 | 1 | 8 - 6 | +2 | 4 | 
| 17 | Atalanta | 3 | 1 | 1 | 1 | 2 - 5 | -3 | 4 | 
| 18 | Olympique Marseille | 3 | 1 | 0 | 2 | 6 - 4 | +2 | 3 | 
| 19 | Atlético Madrid | 3 | 1 | 0 | 2 | 7 - 8 | -1 | 3 | 
| 20 | Club Brugge | 3 | 1 | 0 | 2 | 5 - 7 | -2 | 3 | 
| 21 | Athletic Club | 3 | 1 | 0 | 2 | 4 - 7 | -3 | 3 | 
| 22 | Eintracht Frankfurt | 3 | 1 | 0 | 2 | 7 - 11 | -4 | 3 | 
| 23 | Napoli | 3 | 1 | 0 | 2 | 4 - 9 | -5 | 3 | 
| 24 | Union Saint-Gilloise | 3 | 1 | 0 | 2 | 3 - 9 | -6 | 3 | 
| 25 | Juventus | 3 | 0 | 2 | 1 | 6 - 7 | -1 | 2 | 
| 26 | Bodø / Glimt | 3 | 0 | 2 | 1 | 5 - 7 | -2 | 2 | 
| 27 | Monaco | 3 | 0 | 2 | 1 | 3 - 6 | -3 | 2 | 
| 28 | Slavia Praha | 3 | 0 | 2 | 1 | 2 - 5 | -3 | 2 | 
| 29 | Pafos FC | 3 | 0 | 2 | 1 | 1 - 5 | -4 | 2 | 
| 30 | Bayer 04 Leverkusen | 3 | 0 | 2 | 1 | 5 - 10 | -5 | 2 | 
| 31 | Villarreal | 3 | 0 | 1 | 2 | 2 - 5 | -3 | 1 | 
| 32 | FC København | 3 | 0 | 1 | 2 | 4 - 8 | -4 | 1 | 
| 33 | Olympiacos F.C. | 3 | 0 | 1 | 2 | 1 - 8 | -7 | 1 | 
| 34 | Kairat | 3 | 0 | 1 | 2 | 1 - 9 | -8 | 1 | 
| 35 | Benfica | 3 | 0 | 0 | 3 | 2 - 7 | -5 | 0 | 
| 36 | Ajax | 3 | 0 | 0 | 3 | 1 - 11 | -10 | 0 |