Jack Della Maddalena vs Islam Makhachev Odds and Prediction for UFC 322 fight
By Deniss Novickis | Published: November 12, 2025
Madison Square Garden in New York is the place for UFC 322, which is headlined by two title bouts. Jack Della Maddalena will defend his welterweight championship for the first time against Islam Makhachev, who vacated his lightweight title to move up a weight class. In the co-main event, Valentina Shevchenko puts her flyweight championship belt on the line against Zhang Weili, as the Chinese has vacated her strawweight title that Mackenzie Dern won recently.
MightyTips presents UFC 322 betting predictions and tips for the tournament in the Empire City. We are looking for value spots in terms of betting, so there will be some bouts where we'll suggest passing, albeit still giving a prediction on the outcome.

Thе UFC 322 card is arguably the most stacked one of the year, as it features Sean Brady, Leon Edwards, Benoit Saint-Denis, Bo Nickal, Gregory Rodrigues, Erin Blanchfield, Kyle Daukaus, and many other familiar names. Here's the full schedule of the event in New York:
Check our UFC 322 betting tips, as we start with the main event and go the whole way down to the early preliminaries. Please remember that you must learn to avoid betting on all fights on the card and choose the premium options only to have good long-term results.
Makhachev's decision to move up to welterweight is a daring one, and it certainly carries risks. He's yet to face an opponent who hits with the precision and power that Della Maddalena possesses. Still, Makhachev remains the clear favourite, largely due to his world-class grappling and calmness in high-pressure moments.
Della Maddalena is most dangerous in the early exchanges: his crisp, accurate boxing has the potential to flip the fight in an instant. For Makhachev, the obvious strategy is to close the distance quickly and bring the fight to the mat. If he gets drawn into an early striking battle, a major upset could be on the horizon. Yet we opt for the Dagestani and believe that he'll find a submission.
Prediction: Islam Makhachev by brabo or rear-naked choke, likely in the first half of the fight.
The Garden has seen legends.
Islam Makhachev is here to add his name to the list. 🏆 pic.twitter.com/xSl8GFiYfT
— NEW YORK KNICKS (@nyknicks) November 9, 2025
This fight looks as evenly matched as they come. Zhang Weili's recent performances have highlighted her superior ground control and nonstop tempo, but pulling that off against Valentina Shevchenko is an entirely different task. Zhang is likely to start fast, pressing forward to close the distance and challenge Shevchenko's composure in the clinch. Both women are tough, technical, and mentally sharp, so a full five-round battle seems very possible. Given her current form and determination to make a statement, we see Zhang Weili as the more likely winner here.
Prediction: Zhang Weili by a close, might be even a split decision.
Michael Morales took UFC by storm – the undefeated Ecuadorian has six victories in the promotion, four of them by TKO. However, just look at the opposition. Only Gilbert Burns is a noticeable name, and he is far from his best nowadays. Brady is a totally different animal. What's even more important, Morales never faced a grappler of such class, and we have no idea about his defence against takedowns. We believe that Brady has a clear path to victory here, while striking with Morales could easily lead to the second knockout loss of his career. As there's no reason to doubt Brady's fight IQ, we are going with him winning by decision or submission.
Prediction: Sean Brady gives Morales his first defeat, let's say via a submission.
Let's be honest - when at his best, Edwards should have the striking advantage over Prates, as Ian Machado Garry clearly demonstrated the blueprint back in April. However, Edwards seemed to give up in his last outing mentally, and with two straight losses behind him, the pressure is mounting. A third defeat could see him slip into gatekeeper territory rather than remain a legitimate contender. The outlook isn't encouraging for the Brit. Though he's never been knocked out, even Nate Diaz managed to shake him with a clean shot. Prates, on the other hand, is on the rise and comes forward aggressively from the first seconds. His cardio held up well against Machado Garry, where he even took the fifth round convincingly. While this matchup could turn into a tight contest, the momentum and confidence lean toward Prates.
Prediction: Carlos Prates wins by KO/TKO.
CARLOS PRATES FIGHT WEEK 🇧🇷🇧🇷 pic.twitter.com/IxxcIlJPSC
— Richard sanchez fan account (@tomas_akde) November 10, 2025
The main card starts with a clash of two ranked opponents in the lightweight division. Saint-Denis is back on track, winning his last two fights via submission. He won't need any grappling against Dariush, though, as striking should bring him another victory. Five out of six losses suffered by the American came via knockouts, and his chin is precarious to say the least. Saint-Denis once said that he wants to grapple with any opponent, but it would be a fatal error in this case. On the other hand, jumping forward and pressuring Dariush early should lead the Frenchman to a knockout victory.
Prediction: Saint-Denis celebrates his third victory in a row, this time by knockout.
Nickal's hype train is derailed, but he still somehow headlines the prelims and was on the main card at some point. The UFC still believes in him, and that's why his next opponent is Vieira. The latter is a Brazilian Jiu-Jitsu expert, but he simply can't strike. Andre Petroski outstruck him in February, and that speaks for itself. Nickal is an elite grappler, but in this fight, his game plan must be the same as it was against Paul Craig. If he decides to go to the mat, that might lead to big problems. While a simple decision victory is on the cards for the American, his last will-less loss makes us skip this bout in terms of betting.
Prediction: Bo Nickal wins by unanimous decision.
One of the favourites for the Fight of the Night award, as both athletes bring incredible power and technique to the cage. Kopylov must redeem himself after a very poor performance against Paulo Costa. Rodrigues was knocked out by Jared Cannonier in February, but returned in the summer with a brutal KO of Jack Hermansson. This fight opened up at even odds, but Robocop is a heavy favourite now. The value is clearly on Kopylov, as the Brazilian is very hittable and forgets about defence quite often. If Rodrigues decides to grapple, Kopylov might be in trouble. However, Robokop tends to keep it on the feet, and Kopylov should find a lethal blow at some point.
Prediction: Roman Kopylov by knockout in the first half of the fight.
Cage side angle of Gregory Rodrigues’ KO of Jack Hermansson!! Nasty work!!#UFC317
— Ezee (@EzeemmaCraic) June 29, 2025
This is actually a rematch, as Cortez handed Blanchfield the first defeat of her career by split decision in February 2019. Blanchfield is a clear favourite this time round for a reason. She is much more experienced nowadays and will control this fight from the first minute. Arguably, Blanchfield is better everywhere, even though Cortez is a decent fighter herself, and she has never been finished. All of this makes us believe that Blanchfield will win a decision, getting one step closer to the desired title shot.
Prediction: Erin Blanchfield by a 30-27 decision.
Two bantamweight prospects square off in this bout as Wellmaker is looking for a third first-round knockout in a row in the UFC. He was supposed to fight Serhiy Sidey, but the latter withdrew due to injury, and Haddon stepped in on a 4-week notice. The Australian had just one fight in the UFC, beating a low-class opponent in Dan Argueta via unanimous decision. That was more than a year ago, and he hasn't fought since. We expect striking fireworks here, and Wellmaker, who'll be significantly bigger, should get his hand raised. If you want to add some meat to the bone, bet the American to win by knockout, but we go with a safer option of choosing his victory by any method at 1.66.
Prediction: Malcolm Wellmaker keeps his knockout streak going.
Three undefeated fighters coming into UFC 322:
:flag-ec: Michael Morales (18-0)
:ru: Baysangur Susurakaev (10-0)
:us: Malcolm Wellmaker (10-0)Love the mix of talent they’ve stacked on this card pic.twitter.com/Js3NEMDksI
— Full Violence ™ (@Full_Violence) November 11, 2025
All seasoned MMA bettors know this rule: do not bet on GM3 and do not bet against GM3. Meerschaert had many surprise victories as an underdog and also lost plenty of fights where he looked like an obvious winner. However, time is taking over the 37-year-old, who is on a 3-fight losing streak and was knocked out only three months ago. Daukaus looks like a different man after returning to the UFC. He is better than his opponent in every aspect, and he will find a finish here, most likely via KO/TKO.
Prediction: Kyle Daukaus will knock Meerschaert out.
Here's an interesting one, as an elite grappler, Sabatini, faces Mariscal, who prefers to strike. While Sabatini's chin remains questionable, he definitely can take Mariscal down and control him on the mat for the majority of the fight. Mariscal has never lost by a submission, yet everything comes to an end at some point. He will still have a puncher's chance, as all three rounds start standing, but we suppose that grappling should prevail in this one.
Prediction: Pat Sabatini by a 30-27 or 29-28 decision.
This is another one where we just can’t see any valuable betting spots. The 40-year-old Hill is facing Klein, who is 15 years younger and has all the tools to become a stronghold in the strawweight division. Hill has never been knocked out, but Klein has a chance to be the first one. Klein winning at 1.20 is destined to hit, and you might want to use it as a parlay piece. However, we’ll opt for a pass. It’s women’s MMA, after all.
Prediction: Fatima Klein wins a 30-26 decision, yet we do avoid betting this one.
Khamzat Chimaev's sparring partner came to the UFC via Dana White Contender Series in August, and his second bout in the promotion is once again taking place at a great event. Susurkaev is clearly seen as a future star, and the UFC do all they can to make a safe path for him to the rankings. The Chechen fighter will be punished for showmanship at some point in his career, but it won't happen this time, as the opposition is nowhere near as good. We suggest passing this one in terms of betting.
Prediction: Baisangur Susurkaev by an early knockout, but pass it the choice here.
Two fights...ONE WEEK! 😳
Is Baisangur Susurkaev the next undefeated phenom in the UFC? ⏱️ @vechainofficial #UFC322 pic.twitter.com/d2uqRC9kOp
— UFC Europe (@UFCEurope) November 10, 2025
Camilo was scheduled to fight Abdul-Kareem Al-Selwady at UFC 321 less than a month ago, but that fight was cancelled. The Jaguar should be in good form, and now he is up against Borschev, who steps in on short notice. Borschev is on a 2-fight losing streak and will fight to stay in the UFC. This is a very simple one, and we were a bit surprised by the odds. Slava Klaus is a good striker, but he has zero takedown defence. Camilo, on the other hand, has decent takedowns and has already won by submission twice in his career. He will take Borschev down and should find a finish - either by SUB or ground& pound. Simply bet that the Brazilian will win by any method.
Prediction: Camilo’s victory by submission.
We provide daily predictions and betting tips for many sports events in our free Telegram channel. Join us today to never miss any part of the action!
More news
Jack Della Maddalena vs Islam Makhachev Odds and Prediction for UFC 322 fight
2025 ATP Finals betting odds, player analysis & prediction
Leon Edwards vs Carlos Prates Odds and Prediction for UFC 322 fight
Grand Slam of Darts 2025 Betting Preview
Valentina Shevchenko vs Zhang Weili Prediction: Odds & Analysis for UFC 322 Fight
The fear of high odds in sports betting