Jack Della Maddalena vs Islam Makhachev Odds and Prediction for UFC 322 fight

UFC 322 is set to deliver the heat on November 15 at Madison Square Garden in New York. Jack Della Maddalena will put his welterweight title on the line against Islam Makhachev. The former lightweight champion moved up a division after vacating his belt in May 2025. Now he aims to become a two-division great. Standing in his way is the Australian knockout master, who hasn't tasted defeat in almost 10 years.

In this article, we at MightyTips look at the Della Maddalena vs Makhachev odds, closely analyse both fighters and their chances of winning, to deliver you a prediction on the outcome.

Bookmakers clearly favour Islam, as the odds on Makhachev winning sit around 1.40. It looks like bookies are confident in his capabilities and wrestling dominance. Meanwhile, odds on Della Maddalena winning are 3.00. It's a solid value for those backing the Australian striker.

Jack Della Maddalena is four years younger and holds a 2.3-inch reach advantage. He fights from a switch stance, allowing him to mix up various striking combinations from either side. Islam Makhachev, a former lightweight, once revealed that he walks around at 180-190 lbs when out of competition. This makes his weight cut far less gruelling and should leave him with more energy for the fight.

Islam Makhachev represents the new generation of Dagestani dominance inside the UFC. A lifelong student and training partner of Khabib Nurmagomedov, he built his career on grappling, control, and world-class combat sambo. Now 27-1, Makhachev has cleared the lightweight division, beating top fighters like Charles Oliveira, Dustin Poirier, and Dan Hooker. His ground game is one of the strongest on the roster right now. Once he gains top control, it seems like there's no escape for anyone.

The key difference between Islam and his mentor, Khabib, is striking. Makhachev shows far more precision and technique when on his feet. His head-kick knockout of Alexander Volkanovski in their second fight perfectly showcased that. Still, Islam is not a true power puncher, and his chin hasn't been tested that much yet.

Jack Della Maddalena is a dynamic striker with real finishing power. He's a beast when pressuring opponents, constantly shifting angles and landing strike combinations from both sides. His boxing is built around precise timing and power shots. Although he's not primarily a grappler, the champion has shown great awareness on the mat. He's capable of defending takedowns and can find his way out of submissions.

Della Maddalena's main vulnerability comes from leaving openings when exchanging strikes. He also has previously made some risky grappling choices when under pressure. In the octagon against a guy like Makhachev, there won't be any room for such mistakes. Still, the Australian has proven he can adapt and find his way to win a fight under various circumstances.

Moving up to welterweight is a bold move for Islam Makhachev, and it comes with real risk. He's never been hit by someone with the kind of precision and power that Jack Della Maddalena brings. Absorbing strikes from true 170-pounders is a different challenge entirely. Still, Makhachev enters as a strong favourite thanks to his elite grappling and composure under pressure. 

Della Maddalena, however, is dangerous early. His sharp boxing and accuracy could turn the fight 180 degrees if he connects clean. We've seen how similar odds played out in Ankalaev vs Pereira 2. Makhachev's best path is to close the distance quickly and control the ground. If he gets caught trading early, we might witness one of the biggest upsets of the year.

Both fighters have a real chance to get the job done, but Islam Makhachev should still have the edge with his grappling and control. For those looking for higher value, Makhachev to win by submission is the optimal pick on the board.

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