Lazio vs Roma prediction 21.09.2025 | Serie A

Lazio

Lazio

Kick off:

Date:

AS Roma

AS Roma

1

3.01

X

3.14

2

2.59

  • Competition: Serie A
  • Date: 21st September 2025
  • Kick-off: 11:30 UK / 12:30 CEST
  • Venue: Stadio Olimpico

An intriguing match awaits this Sunday at Stadio Olimpico when Lazio and Roma face off in Derby della Capitale. This is the fourth Serie A fixture for both teams this season, and their third head-to-head meeting in 2025. Read our Lazio vs. Roma preview for predictions and the latest team news.

Lazio vs AS Roma Head to Head (H2H) stats

  1. Lazio

    1 : 1

    AS Roma

    Serie A

  2. AS Roma

    2 : 0

    Lazio

    Serie A

  3. AS Roma

    1 : 0

    Lazio

    Serie A

  4. Lazio

    1 : 0

    AS Roma

    Coppa Italia

  5. Lazio

    0 : 0

    AS Roma

    Serie A

  6. Lazio

    1 : 0

    AS Roma

    Serie A

The two sides have gone head to head eight times since 2022 with all but one of those meetings coming in the Italian top flight. The results have been fairly balanced, with both sides winning three games each and two ending in a draw. This series of matches lacked entertainment as the average number of goals per game was just 1.37.

Lazio

Lazio team overview

After missing out on a place in Europe for the first time in six seasons last year, Lazio would have entered the 2025-26 campaign hoping to make amends, but their performances have been disappointing.

The Eagles began their campaign with a 2-0 defeat to Como and, while they responded with a 4-0 win over Hellas Verona on matchday two, their problems were visible once again in the 1-0 defeat to Sassuolo last weekend.

However, head coach Maurizio Sarri will get motivation from how well Lazio have been at home over the last couple of months, losing only one of the last nine games at this ground.

Patric has not featured this season due to a hamstring injury, and Sunday’s game comes too soon for him. The hosts' injury concerns also include Matías Vecino, Nicolò Rovella, Manuel Lazzari and Samuel Gigot.

Last matches of Lazio

  1. Sassuolo

    1 : 0

    Lazio

    Serie A

  2. Lazio

    4 : 0

    Hellas Verona

    Serie A

  3. Como

    2 : 0

    Lazio

    Serie A

  4. Galatasaray

    2 : 2

    Lazio

    Club Friendlies 1

  5. Fenerbahce

    1 : 0

    Lazio

    Club Friendlies 1

Lazio lineup

Goalkeeper

  • 94

    Ivan Provedel

Defenders

  • 17

    Nuno Tavares

  • 13

    Alessio Romagnoli

  • 34

    Mario Gila

  • 77

    Adam Marušić

Midfielders

  • 7

    Fisayo Dele-Bashiru

  • 6

    Nicolò Rovella

  • 8

    Mattéo Guendouzi

Forwards

  • 10

    Mattia Zaccagni

  • 11

    Valentín Castellanos

  • 22

    Matteo Cancellieri

AS Roma

Roma team overview

Roma finished in the top six for the fourth consecutive season last year and have made a stronger start than their hosts to the 2025–26 Serie A campaign.

I Giallorossi kicked off their season with back-to-back 1:0 wins, beating Bologna at home and Pisa on the road. Eager to secure a third consecutive victory, Gian Piero Gasperini’s team hosted Torino on Sunday. Despite controlling 73% of possession and taking 22 shots, they ultimately lost 1-0.

Paulo Dybala was substituted at the start of the second half due to injury, ruling him out of the Derby della Capitale. The visitors' injury concerns also include Aston Villa loanee Leon Bailey, Mario Hermoso and Edoardo Bove.

Last matches of AS Roma

  1. AS Roma

    0 : 1

    Torino

    Serie A

  2. Pisa

    0 : 1

    AS Roma

    Serie A

  3. AS Roma

    1 : 0

    Bologna

    Serie A

  4. AS Roma

    2 : 2

    NEOM SC

    Club Friendlies 1

  5. Everton

    0 : 1

    AS Roma

    Club Friendlies 1

AS Roma lineup

Goalkeeper

  • 99

    Mile Svilar

Defenders

  • 22

    Mario Hermoso

  • 23

    Gianluca Mancini

  • 5

    Evan Ndicka

Midfielders

  • 43

    Wesley França

  • 35

    Tommaso Baldanzi

  • 17

    Manu Koné

  • 4

    Bryan Cristante

  • 3

    Angeliño

Forwards

  • 18

    Matías Soulé

  • 11

    Evan Ferguson

Prediction

Although Roma have won two of their three games this season, their form is not far off that of the visitors, and previous meetings between the two sides have tended to be close affairs. Lazio have lost only one of their last nine home games, and Roma have lost just one of their last 12 away Serie A matches — both of which are further reasons to expect a close game. I am tipping a low-scoring draw.

Three reasons we expect under 2.5 goals in this game

  1. Five of the last seven home games of Lazio ended with under 2.5 goals.
  2. All the last four Serie A games of Roma ended with under 2.5 goals.
  3. Five of the last seven league games of Lazio ended with under two goals.

Main prediction Lazio - AS Roma

Under 2.5 goals

Updated

clock
winrate

59% winrate

wins

3 wins in a row

Strategic Betting Analyst: Expert in Developing and Implementing Data-Driven, Profitable Sports Betting Strategies.

Best Odds:

Megapari

1.68

Bet here

Lazio vs AS Roma standings in Serie A

Regular Season P W D L
G - A
GD Pts
1 Juventus 4 3 1 0 8 - 4 +4 10
2 Milan 4 3 0 1 7 - 2 +5 9
3 Napoli 3 3 0 0 6 - 1 +5 9
4 Cremonese 3 2 1 0 5 - 3 +2 7
5 Cagliari 4 2 1 1 5 - 3 +2 7
6 Udinese 4 2 1 1 4 - 5 -1 7
7 Roma 3 2 0 1 2 - 1 +1 6
8 Bologna 4 2 0 2 3 - 3 0 6
9 Atalanta 3 1 2 0 6 - 3 +3 5
10 Como 3 1 1 1 3 - 2 +1 4
11 Torino 3 1 1 1 1 - 5 -4 4
12 Lazio 3 1 0 2 4 - 3 +1 3
13 Sassuolo 3 1 0 2 3 - 5 -2 3
14 Inter 3 1 0 2 9 - 6 +3 3
15 Hellas Verona 4 0 3 1 2 - 6 -4 3
16 Genoa 4 0 2 2 2 - 4 -2 2
17 Fiorentina 3 0 2 1 2 - 4 -2 2
18 Pisa 3 0 1 2 1 - 3 -2 1
19 Parma 3 0 1 2 1 - 5 -4 1
20 Lecce 4 0 1 3 2 - 8 -6 1

Lazio vs Roma – FAQ

? Where to watch?

You can watch Sunday’s Serie A encounter between Lazio and Roma on Sofascore.

? What is the average number of corner kicks Lazio have won per game this season?

5.00

? What is the average number of yellow cards Roma have received in their Serie A away encounters this season?

1.33