Genoa vs Empoli Prediction 25.09.2025 | Coppa Italia

The third consecutive term in Serie A did not start in an ideal way for the Genoese, who were able to eke out a meager two points from their opening four league matches, which practically means they remain among the few sides yet to taste the sweetness of victory.

Rossoblu’s only shining moment early in the 2025–26 season came when they routed Lanerossi Vicenza 3-0 in the first round of the Coppa Italia, and they will now look to regain lost confidence from another strong cup performance.

To fight for a better spot in the standings and stay competitive in the upcoming league matches, the club from Liguria must find more fire upfront, as they managed to hit the back of the net just twice in their opening four Serie A games.

Backup goalkeeper Benjamin Siegrist, along with summer loan signings Jean Onana and Maxwel Cornet, will miss Thursday’s cup tie as all three are sidelined with various injuries.

After finishing last season as one of the three teams relegated from Italy’s top flight, Empoli’s early attempts to reclaim their elite status have faltered, yielding just four uninspiring points from as many second-tier clashes.

Before kicking off their Serie B campaign, the Azzurri of Empoli struggled to secure progress in the second round of the Coppa Italia, needing penalties to edge past Reggiana, but they will now look to replicate last season’s impressive run that carried them to the semifinals before eventual winners Bologna ended their journey.

The path to the third round of the national cup might be complicated, with the Tuscan side struggling badly on their early trips this season, losing to both Reggiana and Pescara and letting in seven goals across those outings.

Head coach Guido Pagliuca has a full squad at his disposal apart from midfield duo Duccio Degli Innocenti and Nicolas Haas, who are dealing with serious injuries and face a long road back.