Harrison vs Nunes Odds and Prediction for UFC 324 fight

Amanda Nunes is making a shock return at UFC 324 in Las Vegas. The greatest women's fighter in the history of UFC is stepping out of retirement to face Kayla Harrison, a two-time Olympic gold medallist who has stormed into the UFC and taken over the bantamweight division. Harrison debuted in 2024 and immediately looked like a problem for everyone, ripping the title away from Julianna Peña in her recent bout.

Amanda announced her retirement back in 2023, vacating both the bantamweight and featherweight titles. Now, Kayla has clearly caught her attention. In this Nunes vs Harrison prediction, we break down the betting odds and predict whether Harrison can defend her belt against the GOAT.

It's hard to label either woman as past her prime, but this is still a matchup between two fighters on the far side of 35, where small physical edges start to matter more. The height is identical, yet Nunes holds a three-inch reach advantage over Harrison.

The Lioness has been out for over two years, which is a long time away from the cage, even for someone of her status. Still, we all know exactly what Amanda is capable of. She has beaten every major name in the UFC women's divisions: Valentina Shevchenko, Ronda Rousey, Cris Cyborg, and this list genuinely goes on. Nunes also avenged her shocking loss to Julianna Peña to reclaim the bantamweight title. She remains the only woman in UFC history to hold two titles simultaneously.

Stylistically, Nunes is a dangerous and complete fighter. She carries real knockout power and sharp timing, but her game doesn't stop on the feet. She also owns a strong wrestling and jiu-jitsu base, averaging close to three takedowns per fight. Nunes is taking this fight seriously. She even brought Larissa Pacheco, the only fighter to defeat Harrison during her PFL run, to her training camp to help simulate Harrison's fighting style.

Amanda Nunes didn’t just dominate divisions she erased eras.Began from bantamweight to featherweight...and she defeated legends,champions,and challengers with unmatched power,heart...and fight IQ.

Amanda Nunes redefined what greatness looks like in women’s MMA,standing tall as… pic.twitter.com/BehhUfWGTY

— Diego (@woza_diego) December 19, 2025

Nunes' last fights

Harrison has hit the ground running since arriving in the UFC. Three fights in, she's already beaten some of the toughest names in the division: Holly Holm, Ketlen Vieira, and Peña, walking away with the bantamweight title. That rise shouldn't surprise anyone who knows her background. Harrison is a two-time Olympic gold medallist and the most accomplished American judoka the sport has ever produced.

The striking is still the big question mark. It's functional, but nowhere near the sharpest in the division. That could be a problem against a puncher like Nunes. But once Harrison commits to the takedown, things change fast. Her double legs are brutal, her control is heavy, and she's relentless on the mat. With eight submission wins on her record, if Harrison can get this fight to the ground, she's in a very strong position.

Kayla Harrison grinding hard for her next fight against Amanda Nunes 🔥💪

Via: @KaylaH pic.twitter.com/LbQ7UaX5IX

— Red Corner MMA (@RedCorner_MMA) December 12, 2025

Harrison's last fights

This is a true legacy fight. Without the retirement gap, Nunes would almost certainly be the favourite here. Harrison is facing the toughest challenge of her career, and while she's an absolute monster on the ground, this isn't a matchup where takedowns come easy. Nunes is strong in the clinch, solid defensively, and more than capable of stuffing shots or scrambling back to her feet. If Amanda can keep this fight standing for extended stretches, her striking could be decisive. Expect plenty of clinching and grappling early, but experience matters in moments like this. We're backing Nunes to find a way and get her hand raised.

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