Salford City vs Leyton Orient Prediction 05.12.2025 | FA Cup

Salford’s hopes of lifting a EFL Trophy this season took a heavy blow midweek, as they suffered a humiliating 7-2 defeat at the hands of Rotherham, leaving their loyal supporters reeling. This outcome was particularly bitter considering the Ammies had navigated the group stage of the tournament with a perfect record of three wins from three.

The crushing loss further highlighted the fragility of Salford’s defensive line, which has recently resembled little more than a sieve. The team has conceded at least two goals in five of their last five matches across all competitions, exposing serious vulnerabilities at the back.

Recent form also raises doubts over their ability to secure a positive result against another third-tier opponent, as they have found themselves on the losing side in three of their last four outings. A swift response will be essential ahead of Friday’s FA Cup clash.

Adding to the challenge, experienced right-back Ollie Turton is sidelined with a meniscus injury, a major blow to an already porous backline, while midfielder Josh Austerfield is also out with an ankle issue.

In the manner of their Friday hosts — though less painfully — Leyton Orient have also seen their EFL Trophy journey come to an end, falling narrowly to Plymouth Argyle courtesy of a late winner that left supporters reeling in disbelief.

With one of England’s cup competitions now behind them, the O’s are turning their full attention to the FA Cup, aiming to at least replicate last season’s impressive run when they reached the fourth round and faced Manchester City, putting up a spirited fight before ultimately going down 2-1.

However, head coach Richie Wellens has voiced some concern over his team’s recent away form, having watched his side return from four of their last six road trips across all competitions with heads bowed and points left behind.

On the injury front, Leyton Orient head into Friday’s clash with a fully fit squad, free from any new concerns, meaning Wellens can call upon his entire roster as he demands maximum effort from his players in pursuit of cup glory.