Newcastle United vs PSV Eindhoven Prediction 21.01.2026 | UEFA Champions League

Newcastle United head into this midweek European showdown against the Eindhoven giants aiming to put a frustrating dip in form behind them, having gone three consecutive matches without a victory in regulation time (D2 L1).

Currently occupying eighth place in the Premier League standings, the Magpies have struggled to establish domestic rhythm, a trend that was once again evident in their most recent league outing, where they were held to a drab goalless draw away at Wolves — a result that underlined their ongoing attacking inefficiency.

To their credit, continental competition has offered a measure of relief this term. Eddie Howe’s side currently sit in a respectable 12th position in the league-phase table, just two points adrift of the automatic qualification places for the last 16.

Aside from a comprehensive collapse against the formidable Manchester City, Newcastle have been largely disciplined and resilient at St James’ Park, with that defeat marking their first home loss after an impressive run of 13 unbeaten matches on home soil, including 11 victories.

However, a significant injury crisis continues to hinder their push toward a top-eight finish in the league phase. Key defensive figures such as Dan Burn, Fabian Schar, Jamaal Lascelles, Tino Livramento, and Emil Krafth all remain sidelined, leaving Howe with limited options at the back ahead of this crucial contest.

Meanwhile, PSV Eindhoven make the trip to St James’ Park in buoyant spirits, having established a commanding grip on the Eredivisie summit and firmly set their sights on another domestic title. An outstanding league campaign has seen the Dutch champions collect 17 wins from 19 matches (W17, D1, L1), underlining their dominance on the national stage.

Head coach Peter Bosz has unmistakably embedded a high-tempo, attack-minded philosophy, evident throughout the season and carried seamlessly into the opening weeks of 2026. PSV began the new year by dismantling Excelsior 5-1 at home before edging Fortuna Sittard 2-1 away, results that stretched their advantage over nearest challengers Feyenoord to a staggering 16 points.

While qualification for the knockout stages is not yet mathematically secured, the Boeren have proven remarkably resilient on their travels in this season’s Champions League. They remain unbeaten away from home in the league phase (W1, D2), a run highlighted by a memorable 4-1 demolition of Liverpool at Anfield — a statement performance that resonated across Europe.

However, Bosz faces notable selection challenges ahead of his side’s final league-phase fixture. Injuries rule out Sergino Dest, Ruben van Bommel, and a trio of forwards in Ricardo Pepi, Myron Boadu, and Alassane Pléa, while Ismael Saibari will miss the trip through suspension after accumulating too many yellow cards.