Contents
- Competition: EFL Cup
- Date: Tuesday, 23rd September 2025
- Kickoff: 20:00 UK / 21:00 CEST
- Venue: Anfield (Liverpool)
On Tuesday night at Anfield, Liverpool will host Southampton in an intriguing EFL Cup tie. Arne Slot's team is in excellent form this year and will surely aim for victory in the upcoming clash, but can the Saints shockingly stop them? Bookies certainly see Liverpool as a huge favorite for Tuesday. Let's break down the matchup and find out the best betting option.
Liverpool vs Southampton Head to Head (H2H) stats
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Liverpool
3 : 1
Southampton
Premier League
-
Southampton
1 : 2
Liverpool
Carabao Cup
-
Southampton
2 : 3
Liverpool
Premier League
-
Liverpool
3 : 0
Southampton
FA Cup
-
Southampton
4 : 4
Liverpool
Premier League
-
Liverpool
3 : 1
Southampton
Premier League
Liverpool are usually dominant against Southampton as they have won eight of the last nine H2H matches. The only game in which the club from Anfield failed to win during the span was in 2023, when teams played 4-4. Last season, Liverpool and Southampton met three times, and Arne Slot's team won every time. Another interesting fact about the head-to-head games between these two teams is that four of the previous six matches finished with at least four goals.
Liverpool team overview
Liverpool are undoubtedly one of the best teams in the world and they surely aim for a trophy in every competition they participate in. Arne Slot's team started the season with a defeat in the Community Shield, but after that, the team from Anfield secured six straight victories. In the previous game, they won 2-1 at home against Everton. Slot's team didn't dominate as they used to in that match, but they still recorded another triumph.
Liverpool had a tough seven days in which they played three matches. The head coach admitted that his team ran out of energy against Everton, so we should expect Slot to rotate the squad and rest the leading players in the EFL Cup against Southampton.
Liverpool have some problems with injuries. Stefan Bajcetic, Luke Chambers, and Callum Scanlon are unavailable for the game against Southampton.
Last matches of Liverpool
-
Liverpool
2 : 1
Everton
Premier League
-
Liverpool
3 : 2
Atletico Madrid
Champions League
-
Burnley
0 : 1
Liverpool
Premier League
-
Liverpool
1 : 0
Arsenal
Premier League
-
Newcastle United
2 : 3
Liverpool
Premier League
Liverpool lineup
Goalkeeper
-
25
Giorgi Mamardashvili
Defenders
-
30
Jeremie Frimpong
-
2
Joe Gomez
-
15
Giovanni Leoni
-
26
Andrew Robertson
Midfielders
-
3
Wataru Endo
-
7
Florian Wirtz
-
42
Trey Nyoni
Forwards
-
14
Federico Chiesa
-
22
Hugo Ekitike
-
73
Rio Ngumoha
Southampton team overview
Last season, Southampton played in the Premier League, but they ended at the bottom of the standings and returned to the Championship. Southampton started the 2025/26 season as one of the promotion candidates, but started terribly with only six points in six league matches. In the most recent outing, the Saints lost 3-1 on the road against Hull. The guests had 71% ball possession, but the home side had much better goal-scoring chances, so Southampton again remained empty-handed.
Southampton didn't play well against Hull and the manager, Will Still, was obviously disappointed. He said, "Hull capitalised on what we didn't do very well and scored three goals, but yeah, it's really poor from me, really poor from the team. Not good enough."
Wellington is injured and will not play on Tuesday at Anfield.
Last matches of Southampton
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Hull City
3 : 1
Southampton
Championship
-
Southampton
0 : 0
Portsmouth
Championship
-
Watford
2 : 2
Southampton
Championship
-
Norwich City
0 : 3
Southampton
Carabao Cup
-
Southampton
1 : 2
Stoke City
Championship
Southampton lineup
Goalkeeper
-
31
Gavin Bazunu
Defenders
-
2
Mads Roerslav
-
5
Jack Stephens
-
6
Taylor Harwood-Bellis
-
3
Ryan Manning
Midfielders
-
24
Shea Charles
-
10
Finn Azaz
-
20
Caspar Jander
Forwards
-
18
Tom Fellows
-
42
Damion Downs
-
26
Ryan Fraser
Prediction
Although Liverpool won six matches in a row, they don't seem to be at the top of their form. Arne Slot's team allowed three goals in the previous two games, and the manager admitted they are currently lacking energy. On the other hand, Southampton should be one of the best Championship teams, but they are not playing well at all. Liverpool will likely heavily rotate its squad for Tuesday, so Southampton will have a good opportunity to cover the AH +2 spread.
3 Reasons why Southampton should cover AH +2 spread
- Liverpool allowed three goals in the last two matches
- Liverpool will rest the leading players
- Southampton lost one of the previous four games
Main prediction Liverpool - Southampton
AH2 (+2)
Best Odds: