Liverpool vs Southampton prediction 23.09.2025 | EFL Cup

Liverpool

Liverpool

1 - 0

Half time: 1 - 0

Full time: 1 - 0

Kick off:

Date:

Southampton

Southampton

1

1.26

X

6.80

2

10.60

  • Competition: EFL Cup
  • Date: Tuesday, 23rd September 2025
  • Kickoff: 20:00 UK / 21:00 CEST
  • Venue: Anfield (Liverpool)

On Tuesday night at Anfield, Liverpool will host Southampton in an intriguing EFL Cup tie. Arne Slot's team is in excellent form this year and will surely aim for victory in the upcoming clash, but can the Saints shockingly stop them? Bookies certainly see Liverpool as a huge favorite for Tuesday. Let's break down the matchup and find out the best betting option. 

Liverpool vs Southampton Head to Head (H2H) stats

  1. Liverpool

    3 : 1

    Southampton

    Premier League

  2. Southampton

    1 : 2

    Liverpool

    Carabao Cup

  3. Southampton

    2 : 3

    Liverpool

    Premier League

  4. Liverpool

    3 : 0

    Southampton

    FA Cup

  5. Southampton

    4 : 4

    Liverpool

    Premier League

  6. Liverpool

    3 : 1

    Southampton

    Premier League

Liverpool are usually dominant against Southampton as they have won eight of the last nine H2H matches. The only game in which the club from Anfield failed to win during the span was in 2023, when teams played 4-4. Last season, Liverpool and Southampton met three times, and Arne Slot's team won every time. Another interesting fact about the head-to-head games between these two teams is that four of the previous six matches finished with at least four goals. 

Liverpool

Liverpool team overview

Liverpool are undoubtedly one of the best teams in the world and they surely aim for a trophy in every competition they participate in. Arne Slot's team started the season with a defeat in the Community Shield, but after that, the team from Anfield secured six straight victories. In the previous game, they won 2-1 at home against Everton. Slot's team didn't dominate as they used to in that match, but they still recorded another triumph. 

Liverpool had a tough seven days in which they played three matches. The head coach admitted that his team ran out of energy against Everton, so we should expect Slot to rotate the squad and rest the leading players in the EFL Cup against Southampton. 

Liverpool have some problems with injuries. Stefan Bajcetic, Luke Chambers, and Callum Scanlon are unavailable for the game against Southampton. 

Last matches of Liverpool

  1. Liverpool

    2 : 1

    Everton

    Premier League

  2. Liverpool

    3 : 2

    Atletico Madrid

    Champions League

  3. Burnley

    0 : 1

    Liverpool

    Premier League

  4. Liverpool

    1 : 0

    Arsenal

    Premier League

  5. Newcastle United

    2 : 3

    Liverpool

    Premier League

Liverpool lineup

Goalkeeper

  • 25

    Giorgi Mamardashvili

Defenders

  • 30

    Jeremie Frimpong

  • 2

    Joe Gomez

  • 15

    Giovanni Leoni

  • 26

    Andrew Robertson

Midfielders

  • 3

    Wataru Endo

  • 7

    Florian Wirtz

  • 42

    Trey Nyoni

Forwards

  • 14

    Federico Chiesa

  • 22

    Hugo Ekitike

  • 73

    Rio Ngumoha

Southampton

Southampton team overview

Last season, Southampton played in the Premier League, but they ended at the bottom of the standings and returned to the Championship. Southampton started the 2025/26 season as one of the promotion candidates, but started terribly with only six points in six league matches. In the most recent outing, the Saints lost 3-1 on the road against Hull. The guests had 71% ball possession, but the home side had much better goal-scoring chances, so Southampton again remained empty-handed.

Southampton didn't play well against Hull and the manager, Will Still, was obviously disappointed. He said, "Hull capitalised on what we didn't do very well and scored three goals, but yeah, it's really poor from me, really poor from the team. Not good enough."

Wellington is injured and will not play on Tuesday at Anfield.

Last matches of Southampton

  1. Hull City

    3 : 1

    Southampton

    Championship

  2. Southampton

    0 : 0

    Portsmouth

    Championship

  3. Watford

    2 : 2

    Southampton

    Championship

  4. Norwich City

    0 : 3

    Southampton

    Carabao Cup

  5. Southampton

    1 : 2

    Stoke City

    Championship

Southampton lineup

Goalkeeper

  • 31

    Gavin Bazunu

Defenders

  • 2

    Mads Roerslav

  • 5

    Jack Stephens

  • 6

    Taylor Harwood-Bellis

  • 3

    Ryan Manning

Midfielders

  • 24

    Shea Charles

  • 10

    Finn Azaz

  • 20

    Caspar Jander

Forwards

  • 18

    Tom Fellows

  • 42

    Damion Downs

  • 26

    Ryan Fraser

Prediction

Although Liverpool won six matches in a row, they don't seem to be at the top of their form. Arne Slot's team allowed three goals in the previous two games, and the manager admitted they are currently lacking energy. On the other hand, Southampton should be one of the best Championship teams, but they are not playing well at all. Liverpool will likely heavily rotate its squad for Tuesday, so Southampton will have a good opportunity to cover the AH +2 spread. 

3 Reasons why Southampton should cover AH +2 spread

  1. Liverpool allowed three goals in the last two matches
  2. Liverpool will rest the leading players
  3. Southampton lost one of the previous four games

Main prediction Liverpool - Southampton

AH2 (+2)

Updated

clock
winrate

54% winrate

wins

3 wins in a row

During 15 years of betting, Nemanja gradually improved his skills to help others bet wisely. He's been playing basketball on a youth level, but is interested basically in every sport, especially football and tennis.

Best Odds:

20Bet

1.75

Bet here

Liverpool vs Southampton – FAQ

? Where to watch?

You can find the match officially on the Arena Sport channel.

? How much is the average xG for Liverpool?

The average xG for Liverpool in the Premier League this season is 1.62.

? How much is the average xG for Southampton this season?

The average xG for Southampton in the Championship this season is 1.68.