Cagliari vs Genoa prediction 22.11.2025 | Serie A

Cagliari reached the international break without a win in seven, a run that included four losses and two draws, so the pause probably felt more like a reset button than an interruption.

Their final outing before the break, a goalless draw at the Stadio Giuseppe Sinigaglia, came with just 25 percent possession, their lowest league figure of the season.

Home form has been especially shaky as they lost their last three at the Unipol Domus by a combined score of 6-1. Even so, The Islanders can lean on a small positive because they have not lost any of their last three home games against the Grifone.

Nicola Pintus and Alessandro Deiola remain sidelined with muscle issues, while Andrea Belotti and Giuseppe Ciocci continue their recoveries from ligament and ankle injuries.

Credit to Genoa, they put together a two-match unbeaten streak heading into the international break which saw them defeat Sassuolo before earning a point against Fiorentina after that.

Scoring on two occasions in consecutive matches must have felt like an avalanche of goals to a team that has not done that since May, and The Grifone will be keen to extend that upward trajectory.

But their record away from home makes for concern given they have gone down in three of their last four and conceded exactly two goals in all of the last three.

The trickier part about it is that, Jean Onana and Jeff Ekhator are out as well with muscle and heel issues, which leaves them less flexible in midfield and attack.