Bayer Leverkusen vs PSV Eindhoven prediction 01.10.2025 | UEFA Champions League
Bayer Leverkusen
Kick off:
Date:
PSV Eindhoven
1
1.85
X
3.80
2
3.80
Contents
- Competition: UEFA Champions League
- Date: 1st October, 2025
- Kickoff: 20:00 UK / 21:00 CEST
- Venue: BayArena
The UEFA Champions League group stage continues on the first day of October as Bayer Leverkusen host PSV Eindhoven in what promises to be one of the standout ties of the round.
Leverkusen, one of Germany’s most in-form sides in recent years, are looking to establish themselves among Europe’s elite under a dynamic style of play that has brought domestic success. PSV Eindhoven, meanwhile, arrive with high ambitions of their own, aiming to prove that they can compete with Europe’s biggest clubs after several strong seasons in the Eredivisie. Both teams have failed to win their opening games on matchday one, therefore they should be even more motivated on Wednesday night.
H2H stats
Historically, Bayer Leverkusen and PSV Eindhoven have met only two times in European competition, but their encounters have always been competitive. Most notably, the two clubs faced each other in the first round of the UEFA Cup in the 1994/95 season, with Leverkusen advancing to the next round following a 5-4 aggregate win. Apart from that, it has been more than 30 years since their last meeting.
Bayer Leverkusen team overview
Leverkusen come into this game in solid form, building on a five-match unbeaten run across all competitions. Although the 2024/25 Bundesliga champions opened the season with a 2-1 defeat away to Hoffenheim, they quickly bounced back and regained momentum following the departure of Erik ten Hag. Since then, they have collected seven points from a possible nine in the Bundesliga and produced an impressive comeback in Round 1 of the Champions League, scoring in stoppage time to earn a 1-1 draw against FC Copenhagen. Leverkusen’s home record in Europe has been particularly strong in recent campaigns, having won all four of their group-stage fixtures in the 2024/25 Champions League.
The hosts have four guaranteed absentees ahead of Wednesday: Patrik Schick, Martin Terrier, Exequiel Palacios and Robert Andrich are all unavailable.
Last matches of Bayer Leverkusen
-
St Pauli
1 : 2
Bayer Leverkusen
Bundesliga
-
Bayer Leverkusen
1 : 1
Borussia M`gladbach
Bundesliga
-
FC Copenhagen
2 : 2
Bayer Leverkusen
Champions League
-
Bayer Leverkusen
3 : 1
Eintracht Frankfurt
Bundesliga
-
Werder Bremen
3 : 3
Bayer Leverkusen
Bundesliga
Bayer Leverkusen lineup
Goalkeeper
-
1
Mark Flekken
Defenders
-
4
Jarell Quansah
-
5
Loïc Badé
-
12
Edmond Tapsoba
-
20
Alejandro Grimaldo
-
21
Lucas Vázquez
Midfielders
-
6
Ezequiel Fernández
-
8
Robert Andrich
-
17
Eliesse Ben Seghir
-
10
Malik Tillman
Forwards
-
35
Christian Kofane
PSV Eindhoven team overview
PSV Eindhoven head into this game with mixed emotions. While they have been nearly flawless in the early stages of the Eredivisie season - collecting five wins, one draw, and just a single defeat - their first outing in the 2025/26 Champions League was a major disappointment. Peter Bosz’s side were convincingly beaten 3-1 by debutants Union Saint-Gilloise, managing only a late consolation goal in the final minute of regulation time. That setback appears to have dented the team’s confidence, as reflected in their most recent Eredivisie fixture, where they scraped a narrow 2-1 victory over Excelsior.
The visitors will also head into this fixture without four first team players: Alassane Plea, Kiliann Sildilia, Myron Boadu and Ruben van Bommel are all listed as unavailable.
Last matches of PSV Eindhoven
-
Excelsior
1 : 2
PSV Eindhoven
Eredivisie
-
PSV Eindhoven
2 : 2
Ajax
Eredivisie
-
PSV Eindhoven
1 : 3
Union Saint-Gilloise
Champions League
-
NEC Nijmegen
3 : 5
PSV Eindhoven
Eredivisie
-
PSV Eindhoven
0 : 2
Telstar
Eredivisie
PSV Eindhoven lineup
Goalkeeper
-
32
Matěj Kovář
Defenders
-
8
Sergiño Dest
-
6
Ryan Flamingo
-
4
Armando Obispo
-
2
Anass Salah-Eddine
Midfielders
-
22
Jerdy Schouten
-
23
Joey Veerman
-
10
Paul Wanner
-
5
Ivan Perišić
-
34
Ismael Saibari
Forwards
-
9
Ricardo Pepi
Prediction
This match has all the ingredients for a thrilling Champions League encounter between two sides that thrive on offensive football. Leverkusen’s home advantage and recent form give them the edge, particularly with their ability to control the midfield and create sustained pressure. PSV, however, have the attacking tools to exploit any defensive lapses and will not be overawed by the occasion. Goals are expected from both sides, as recent performances suggest - PSV have scored in all but one match this season, while Leverkusen have been even more consistent, finding the net in every game across all competitions so far.
Three reasons we expect BTTS
- PSV have scored in all but one match so far this season.
- Leverkusen have gone one better, finding the net in every game across all competitions.
- Both teams scored in the opening fixtures of their 2025/26 Champions League campaigns.
Main prediction Bayer Leverkusen - PSV Eindhoven
Both Teams to Score
Best Odds:
22bet
1.55
Bayer Leverkusen vs PSV Eindhoven standings in Champions League
| League Stage | P | W | D | L |
G - A
|
GD | Pts | |
|---|---|---|---|---|---|---|---|---|
| 1 | FC Bayern München | 2 | 2 | 0 | 0 | 8 - 2 | +6 | 6 |
| 2 | Real Madrid | 2 | 2 | 0 | 0 | 7 - 1 | +6 | 6 |
| 3 | Inter | 2 | 2 | 0 | 0 | 5 - 0 | +5 | 6 |
| 4 | Tottenham Hotspur | 2 | 1 | 1 | 0 | 3 - 2 | +1 | 4 |
| 5 | Paris Saint Germain | 1 | 1 | 0 | 0 | 4 - 0 | +4 | 3 |
| 6 | Atlético Madrid | 2 | 1 | 0 | 1 | 7 - 4 | +3 | 3 |
| 7 | Newcastle United | 2 | 1 | 0 | 1 | 5 - 2 | +3 | 3 |
| 8 | Olympique Marseille | 2 | 1 | 0 | 1 | 5 - 2 | +3 | 3 |
| 9 | Sporting CP | 1 | 1 | 0 | 0 | 4 - 1 | +3 | 3 |
| 10 | Club Brugge | 2 | 1 | 0 | 1 | 5 - 3 | +2 | 3 |
| 11 | Arsenal | 1 | 1 | 0 | 0 | 2 - 0 | +2 | 3 |
| 12 | Manchester City | 1 | 1 | 0 | 0 | 2 - 0 | +2 | 3 |
| 13 | Qarabağ | 1 | 1 | 0 | 0 | 3 - 2 | +1 | 3 |
| 14 | FC Barcelona | 1 | 1 | 0 | 0 | 2 - 1 | +1 | 3 |
| 15 | Eintracht Frankfurt | 2 | 1 | 0 | 1 | 6 - 6 | 0 | 3 |
| 16 | Liverpool | 2 | 1 | 0 | 1 | 3 - 3 | 0 | 3 |
| 17 | Chelsea | 2 | 1 | 0 | 1 | 2 - 3 | -1 | 3 |
| 18 | Union Saint-Gilloise | 2 | 1 | 0 | 1 | 3 - 5 | -2 | 3 |
| 19 | Galatasaray | 2 | 1 | 0 | 1 | 2 - 5 | -3 | 3 |
| 20 | Atalanta | 2 | 1 | 0 | 1 | 2 - 5 | -3 | 3 |
| 21 | Bodø / Glimt | 2 | 0 | 2 | 0 | 4 - 4 | 0 | 2 |
| 22 | Borussia Dortmund | 1 | 0 | 1 | 0 | 4 - 4 | 0 | 1 |
| 23 | Juventus | 1 | 0 | 1 | 0 | 4 - 4 | 0 | 1 |
| 24 | Bayer 04 Leverkusen | 1 | 0 | 1 | 0 | 2 - 2 | 0 | 1 |
| 25 | FC København | 1 | 0 | 1 | 0 | 2 - 2 | 0 | 1 |
| 26 | Olympiacos F.C. | 1 | 0 | 1 | 0 | 0 - 0 | 0 | 1 |
| 27 | Slavia Praha | 2 | 0 | 1 | 1 | 2 - 5 | -3 | 1 |
| 28 | Pafos FC | 2 | 0 | 1 | 1 | 1 - 5 | -4 | 1 |
| 29 | Villarreal | 1 | 0 | 0 | 1 | 0 - 1 | -1 | 0 |
| 30 | Benfica | 2 | 0 | 0 | 2 | 2 - 4 | -2 | 0 |
| 31 | PSV | 1 | 0 | 0 | 1 | 1 - 3 | -2 | 0 |
| 32 | Athletic Club | 1 | 0 | 0 | 1 | 0 - 2 | -2 | 0 |
| 33 | Napoli | 1 | 0 | 0 | 1 | 0 - 2 | -2 | 0 |
| 34 | Monaco | 1 | 0 | 0 | 1 | 1 - 4 | -3 | 0 |
| 35 | Ajax | 2 | 0 | 0 | 2 | 0 - 6 | -6 | 0 |
| 36 | Kairat | 2 | 0 | 0 | 2 | 1 - 9 | -8 | 0 |